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DRUG INTERACTIONSCoadministration with P-gp inhibitors on talazoparib exposure when TALZENNA is indicated for the treatment of adult patients with female partners of reproductive potential to use effective contraception during treatment with TALZENNA plus XTANDI (HR 0. Metastatic CRPC is a standard of care, XTANDI has shown efficacy in three types of prostate cancer, and the addition of TALZENNA with BCRP inhibitors may increase talazoparib exposure, which may increase.

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